“I'm running Mac OSX and the genuine Arduino Nano just works. Drivers for the clones that use CH34x interfaces don't open a port without getting into Unix and downloading and installing a driver. Had to go to the dark side (Win 10) for the clones to easily link up.”
“I built my project using clones, due to the initial dangers involved with blowing the arduino up. When I finalised my project I switched out the clone Nano for an original and I am glad I did:
The main benefits (as far as my setup goes) is that the connection to the Nano Serial port via FTDI driver is far more more reliable than the Cloned Nano CH340 driver. Serial readouts are easier to monitor in Arduino IDE, due to how Serial page refreshes. Only drawback vs clones is that the CH340 driver used with the clones allows for multiple connections to be open to the same device via multiple apps, so you can use Serial monitor from a seperate IDE window whilst using another for coding. The original forces you to close the "extra" serial monitor before uploading, but this is a minor... I find the original more responsive overall as well as the millis() function being seemingly more accurate. Overall, I am glad I switched back to the original... The overall board quality is also much better than the clones.”